Episode #14 is now available! Listen on iTunes, Stitcher, SoundCloud, Google Play, and many other podcast platforms.
How do a patient's lifestyle, dietary behavior, and other environmental variables effect colon and rectal cancer treatment?
Medical oncologist, Dr. Kimmie Ng from the Dana Farber Cancer Institute joins the podcast to speak about her work
Stay tuned for new episodes in 2019! Listen to all 13 "How We Treat CRC Podcast" episodes on-the-go or at home on iTunes, SoundCloud, and Stitcher.
You can now view the reference list for our piece on ERAS.
See below to listen, and visit the Episode Library to access them and check out all other episodes.
Drs. Bleday and Meyerhardt speak with Dr. Kevin Elias about "Enhanced Recovery After Surgery" methods and studies taking place right now in reducing stress on the patient's body pre-surgery. Even eating, hydrating, and carbohydrates are involved in prepping for common surgeries CRC doctors will want to learn more about.
Click here to read Kevin's full bio.
To view this episode's references and more information on the studies mentioned in this episode, visit the How We Treat CRC Podcast's episode library on this blog.
Click here to listen on iTunes.
Episode 11 is now available on SoundCloud and iTunes.
First, the team analyzes a case involving rectal cancer in a 65 year old male patient at a team conference. Guests featured in the segment are Dr. Jeff Wisch and Dr. Harvey Mamon.
Second, the podcast is joined by Dr. Rodrigo O. Perez from Brazil who worked on the Watch and Wait approach with Dr. Angelita Habr-Gama. He is an expert on the topic, and shares some of his experiences working with one of the innovators in colorectal cancer treatment.
According to their team's study and paper in Dis Colon Rectum in 2013, "No immediate surgery (Watch and Wait) has been considered in select patients with complete clinical response after neoadjuvant chemoradiation to avoid postoperative morbidity and functional disorders after radical surgery."
Below are some references to the topics discussed in this month's episode. Enjoy!
Brazilian protocol, originally proposed by Habr-Gama in 2006:
https://www.ncbi.nlm.nih.gov/pubmed/16813588/
(Habr-Gama et al., 2010) – follow-up study looking at short term data
https://www.ncbi.nlm.nih.gov/pubmed/20883957
(Habr-Gama et al., 2013) – same group, looking at longer-term outcomes
https://www.ncbi.nlm.nih.gov/pubmed/24022527/
MSKCC protocol (Smith et al., 2012)
https://www.ncbi.nlm.nih.gov/pubmed/23154394
van der Valk’s presentation at ASCO in 2017 re: update from the International Watch & Wait database
http://ascopubs.org/doi/abs/10.1200/JCO.2017.35.4_suppl.521
A recent retrospective study in Dis Colon Rectum that appeared in March 2017 (from Kong and others in Australia) that tracked outcomes with those patients end up needing a salvage operation following “watch and wait”
https://www.ncbi.nlm.nih.gov/pubmed/28177997
Reviews:
A recent review by Habr-Gama and others:
https://www.ncbi.nlm.nih.gov/pubmed/28501249/
Two good review/perspective piece on the topic of watch and wait in this disease:
Torok et al., 2016
https://www.ncbi.nlm.nih.gov/pubmed/26599064
Glynne-Jones and Hughes, 2016
https://www.ncbi.nlm.nih.gov/pubmed/26625960
Episode #9 focuses on Heated Intraperitoneal Chemotherapy (HIPEC) treatment. For those that may be unfamiliar with the topic, HIPEC is a highly concentrated and heated type of chemo directed at the abdomen during surgery. HIPEC differs from more traditional and systemic treatments due to the delivery of drugs into a patient's body. The chemo does not circulate through the entire body during HIPEC. It only delivers directly to the cancerous cells.
The experts joining the podcast to discuss this type of care are Dr. Nelya Melnitchouk and Dr. Tom Abrams from the GI team at the Dana Farber/Brigham and Women's Cancer Center in Boston.
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]]>In the second part of our discussion on colorectal cancer trials, Dr. James Fleshman joins Ron to discuss the ACOSOG Z6051 Randomized Clinical Trial. This surgical trial aims to decipher the differences of open versus laparoscopic surgery in the treatment of colorectal cancer. To read more about Dr. Fleshman's findings and reports click here.
Dr. Fleshman is the Helen and Stanley Joseph Seeger Professor and Chairman, Department of Surgery at Baylor University Medical Center in Dallas. His professional focus is the treatment of patients with colorectal diseases. He has developed an international reputation in the laparoscopic treatment of colorectal cancer and the development of randomized controlled trials to evaluate the use of laparoscopic techniques in the treatment of colorectal cancer. Click here to read a full bio.
In this episode, Jeff and Ron also answer a listener question and discuss the future of patient trials in this field.
Episodes available on iTunes, SoundCloud, and Stitcher.
]]>The How We Treat Colon & Rectal Cancer podcast's next two episodes will feature discussions about clinical trials focused on colorectal cancer treatment. In part one, Dr. Deborah Schrag joins us to provide an inside look at the PROSPECT trial currently taking place.
PROSPECT is the acronym for Preoperative Radiation Or Selective Preoperative Radiation and Evaluation before Chemotherapy and Total Mesorectal Excision (TME). From the on-going trial, Dr. Schrag and her team hope to decipher and compare the results of standard chemo and radiation treatment using a regimen of drugs named FOLFOX (the drugs 5-fluorouracil (5-FU), oxaliplatin and leucovorin). To learn more about this trial, listeners can click here.
Episode #5 is now available on SoundCloud and iTunes. In this episode, our hosts talk over a case with two specialists in immunotherapy from the Dana-Farber: Dr. Osama Rahma and Dr. Matthew Yurgelun. After reviewing the patient and case details, our guests outline the unique set of challenges during treatment due to the patient testing positive for Lynch Syndrome. It is an engaging discussion.
Post your questions and comments here or email howwetreat@gmail.com.
Enjoy!
All How We Treat Colon & Rectal Cancer Podcast episodes are now available on iTunes. Subscribe to the show today, and click here to access the show's iTunes preview page.
Stay tuned for Episode #5 later this month. The discussion topic will be "Immunotherapy." Tweet @RonaldBledayMD or comment on this post with your questions/comments. Ron and Jeff will answer them in the upcoming episode.
In episode 4, the hosts discuss the complications and processes that are involved in treating a frail colorectal cancer patient.
Stay tuned for another podcast episode coming soon.
The How We Treat Colon and Rectal Cancer Podcast's fourth episode will focus on a recent case involving complications due to a patient's age and frailty. The medical experts joining us will be Dr. Nadine Jackson McCleary and Dr. John Saltzman.
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Episode #3 of the podcast is now available.
Join your hosts as they explore a case of upper rectal cancer involving colitis and IBD. This episode's guests are Dr. Joshua Korzenik and Dr. Harvey Mamon. To see references mentioned in and relating to the discussion, visit the Episode Library page on this blog.
Have a question or comment? Leave one on the post or send an email to howwetreat@gmail.com.
In this episode, Dr. Bleday and Dr. Meyerhardt explore the use of imaging during the treatment of a rectal cancer patient. Dr. Michael Rosenthal joins us to discuss this crucial (yet complicated) tool for colorectal cancer doctors.
Click here to access the articles, studies, and other references mentioned in the episode.
Welcome to the podcast!
In our first episode, Dr. Marios Giannakis joins Ronald Bleday for a discussion on the treatment of a colorectal cancer patient involving the use of chemotherapy after rectal cancer surgery.
Have a question or comment? Leave a post below, email alec@outreach.technology, or connect with us at @RonaldBledayMD on twitter.
Finally... Remember to subscribe, and stay tuned for more episodes.
Last month, podcast host Dr. Ronald Bleday and his patient were featured in a story on WBUR. The piece focused on enhanced care methods for his surgery patients.
Click here to listen to the spot.
